* 1019 - Timisoara (as Dibiscos/Bisiskos/Tibiskos/Tibiskon/Timbisko/etc.) is mentioned for the first time in written documents by Byzantine Emperor Basil II (not all historians agree with this identification).
* 1154 - The Arab geographer Sarif al Idrisi, in his work "The book of pleasures", is describing precisely the road from Cavorz (ie Karlowitz/Sremski Karlovci) to Timisoara, passing trough Cnez (ie Satchinez/Knez); he declare that Timisoarais "a pleasant city ... offering big richness".
* 1177 - First mention of the Castrensis de Thymes in a medieval document.
* 1212 - The fort of Timisoara(Castrum Temesiensis) is mentioned in the decree of King Andrew II of Hungary
* 1241 - The town is partly destroyed by the Tatars.
* 1307 - Charles I of Hungary builds the stone fortress and makes the city the capital of his kingdom.
* 1323 - King Charles I of Hungary attends the holy service in Saint George's church [Sfântu Gheorghe]. This church still exists today in Timisoara.
* 1342 - Timisoarawas mentioned for the first time with the title of "civitas" (city).
* 1370 - The first handicraftsmen's guild is documented in Timisoara.
* 1396 - The town is the starting point for the Nicopolis crusade.
* 1478–1494 - Pavel Chinezul becomes county head of Timis, and Captain of Timisoara.
* 1497 - Pelbart of Timisoara, the only author of incunabula in Romania, publishes his works in Basel and later in Hagenau.
* 1514 - Fortress Timisoarais attacked by rebel peasant troops led by George Dozsa (Dozsa György in Hungarian, Gheorghe Doja in Romanian). The revolt was put down and George Dozsa executed in a cruel and unmerciful way (along with others 40,000–60,000 rebel peasants) in Timisoara. Today, on the place of the martyrdom, of the hot throne, there is the statue of Saint Mary, manufactured by architect László Szekély and sculptor György Kiss. According to the legend, during George Dosza's surplice, the Jesuit monks saw in the ear the image of Holy Mary. The first statue was raised here in 1865. The actual monument was raised in 1906.
* 1549 - Opening of the Protestant School in Timisoarafounded and led by István Kiss of Szeged.
* 1552 - Timisoarais conquered by the Ottoman Empire and becomes capital of the Eyalet of Temesvar.
* 1596 - Sigismund Báthory of Transylvania and Michael the Brave of Wallachia fail to capture Timisoaraafter a 40-day siege.
* 1660 - The Ottoman historian, geographer and globetrotter Evliya Celebi (B 1611, D March 1682) visits Timisoara. According to him (in Seyahatname/The book of travels), the locality had more than 36,000 inhabitants (living in 10 suburbs—1500 houses—around the fortress) and the fortress's garrison numbered 10,000 soldiers. In the fortress existed 1200 houses, more than 400 shops, 4 public baths, 3 restaurants and confectioneries, 7 schools.
* 1688 - The East Banat is conquered by the Habsburg Monarchy's general Veterani (born in Venice).
* 1688 - The Turkish garrison of Timisoararises against the Ottoman authorities.
* 1696 - The imperial troops led by Frederick Augustus I besiege Timisoara unsuccessfully.
* 1716 - Prince Eugene of Savoy takes the town from the Turks.
* 1722–1726 - First wave of German colonists (Danube Swabians) under Emperor Charles VI.
* 1728-1771 Digging and regularization of the Bega channel. The Bega was transformed into a navigable fluvial channel (115 km) which connected the Banat with other European riverways. The first attempt to regulate the Bega and Timis, rivers were made under the Ottoman occupation by A. Cornaro when some work was done in the Budint-Chizatau zone. The first steps were made between 1728–1732 under Count Florimund Mercy's leadership.
* 1728 - A tobacco mill is set up in Timisoara. The factory is still functioning.
* 1753 - The first mention of the organized theatre of Timisoara. A German group of actors performed theatre plays in the town between May-November. Timisoarais the third town in the Empire, after Vienna and Budapest with a permanent theatre season.
* 1760 - Timisoarais the first town in the Empire where the public lightening using suet candles and lamps with oil and grease is introduced.
* 1763–1772 - Second wave of German colonization under Empress Maria Theresa of Austria.
* 1782–1786 - Third wave under Emperor Joseph II.
* 1738–1739 - Epidemic of plague.
* 1762–1763 - Epidemic of plague.
* 1771 - The first printing house/owner Mathäus Heimerl in Fabric quarter.
* 1781 - 21 December: Joseph II's decree regarding the privilege of imperial free city Timisoara.
* 1796 - The Magic Flute was performed in Timisoaraone year after its premiere in Vienna.
* 1815 - Printer Joseph Klapka – the future mayor – sets up in Timisoarathe first borrowing library in a Hungarian town.
* 1819 - Joseph Klapka becomes mayor of Timisoara.
* 1823 - November 3: In his letter addressed from Timisoarato his father in Târgu-Mures,, mathematician János Bolyai mentions that he discovered the principles of the Non-Euclidean geometry.
* 1846 - Composer and pianist Franz Liszt halts in Timisoaraand performs three concerts in the Theater's hall.
* 1847 - Johann Strauss II, the "Waltz King", performs in Timisoarawith his orchestra.
* 1849 - Between April 26 and August 8, Timisoarais sieged by Hungarian revolutionary forces (the longest siege of the town).
* 1852 - Timisoarais linked with Vienna trough the telegraph electric line. This is the first line in the territory of present-day Romania.
* 1855 - February 9: Giuseppe Verdi's "La Traviata" opening night in Timisoara.
* 1857 - Public street lighting with aerial gas.
* 1857 - Inauguration of the first railroad in the Banat's plain: Szeged–Kikinda–Jimbolia–Timisoara, 112 km. To travel from Timisoarato Budapest took 26h and from Timisoarato Vienna 36h. The first railroads station is opened in Timisoara.
* 1866 - Alexander John Cuza, Prince of Moldavia and Wallachia stops in Timisoaraon his way into exile. He stays at the "Trompetistul" road house.
* 1869 - First tram with horses (6.6 km).
* 1870 - The first metallic bridge, the Bem bridge, is built on Bega Channel. During the time, only in Timisoara, on Bega were built 71 bridges. Today in Timisoara 13 bridges exist.
* 1879 - Start of the works on the town's telephone network (first 52 subscribers) in Timisoara. The network was built as a private enterprise by Ignatiu Leyritz.
* 1879 - September 15: Recital of Johannes Brahms and Joseph Joachim in Timisoara.
* 1883 - June 5: The Orient Express Train is launched, passing trough Banat: Szeged–Kikinda–Jimbolia–Timisoara–Caransebes,–Ors,ova.
* 1884 - First city in Europe to have public street lighting with electricity.
* 1886 - Set up of the "Ambulance" service of Timisoara. This is the first ambulance station in Hungary and today Romania.
* 1891 - The first permanent museum is opened in Timisoara.
* 1899 - June 25: The first football/soccer mach in today Romania was held in Timisoarabetween the schoolboys of the Piarist High-school lead by Carol Müller, gymnastic professor.
* 1907 - The walls of the fortress are destroyed to allow for new construction.
* 1918 - November 15: Serbian forces enter into the town. The Banat region was desired by both Serbia and Romania.
* 1918 - December 3: French colonial forces arrive to avoid any possible conflicts between Serbia and Romania.
* 1919 - July 28: Romanian administration is installed. Banat is partitioned between Romania (2/3) and Serbia (1/3).
* 1919 - August 3: Romanian army enters Timisoara.
* 1920 - The theater is destroyed by a fire. It will be rebuilt and opened in 1928.
* 1920 - Set up and opening of the Polytechnic School of Timisoara.
* 1921 - George Enescu's first concerts in Timisoara.
* 1921-1927 - The soccer team "Chinezul" from Timisoarais the champion of Romania in 6 consecutive editions of the championship.
* 1926 - The statue of "Lupoaica" ("She-wolf" - Romulus and Remus), a gift from Italian authorities and later the town symbol, is inaugurated in the center.
* 1928 - The first professional soccer club from Romania - "Ripensia" - is founded in Timisoara.
* 1930 - Timisoarahas 91,866 inhabitants (census), was the seventh biggest city in Romania (26% Romanians, 30% Hungarians, 30% Germans, 8% Jewish).
* 1932–1938 - The soccer team "Ripensia" from Timisoarais for the 5th time the champion of Romania.
* 1944 - June 16–17th: the city is bombed for the first time, by Britain's RAF.
* 1944 - July 3: the city is bombed again, by the United States Air Force.
* 1944 - September 12: the Soviet Red Army enters.
* 1945 - The first professional Romanian theatre group is established in Timisoara.
* 1946 - The Romanian Opera is established, and its first performance, in April 1947, is "Aida" by Giuseppe Verdi.
* 1953 - The State Magyar Theater (Teatrul Maghiar de Stat) is established (known since 1990 as Csiky Gergely theatre), as well as the State German Theater (Teatrul German de Stat)
* 1955 - The first radio show broadcast by Radio Timisoara.
* 1969 - Mecipt 1, the first Romanian computer was made in Timisoara.
* 1986 - The Botanic Park is opened in Timisoara. The Zoo is opened in the same year.
* 1989 - 16 December: The Revolution against the communist regime of Nicolae Ceaus,escu begins in Timisoara. On 20 December, Timisoarais declared the first Free Town. 1,104 people died and 3,352 were wounded.
* 1992 - Free and just elections. Viorel Oancea becomes the mayor of Timisoara.